Supported Applications
Manta
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Description
calls structural variants (SVs) and indels from mapped paired-end sequencing reads. Manta is optimized for analysis of germline variation in small sets of individuals and somatic variation in tumor/normal sample pairs. It discovers, assembles, and scores large-scale SVs, medium-sized indels and large insertions within a single efficient workflow. The method is designed for rapid analysis on standard compute hardware: NA12878 at 50x genomic coverage is analyzed in less than 20 minutes on a 20 core server, and most WGS tumor/normal analyses can be completed within 2 hours.
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Usage
To list all executables provided by Manta, run:$ biogrids-list manta
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Installation
Use the following command to install this title with the CLI client:$ biogrids-cli install manta
Available operating systems: Linux 64, OS X INTEL -
Primary Citation*
X. Chen, O. Schulz-Trieglaff, R. Shaw, B. Barnes, F. Schlesinger, M. Källberg, A. J. Cox, S. Kruglyak, and C. T. Saunders. 2016. Manta: rapid detection of structural variants and indels for germline and cancer sequencing applications. Bioinformatics. 32(8): 1220-1222.
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*Full citation information available through
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Keywords
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Default Versions
Linux 64:  1.4.0 (337.2 MB)
OS X INTEL:  1.4.0 (295.9 MB) -
Developers
Christopher T Saunders