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  • Description

    is a fast and sensitive variant-caller for inferring SNVs and indels from next-generation sequencing data. It makes full use of base-call qualities and other sources of errors inherent in sequencing (e.g. mapping or base/indel alignment uncertainty), which are usually ignored by other methods or only used for filtering.

  • Usage

    To list all executables provided by LoFreq, run: $ biogrids-list lofreq Copy to clipboard
  • Installation

    Use the following command to install this title with the CLI client: $ biogrids-cli install lofreq Copy to clipboard Available operating systems: Linux 64, OS X INTEL
  • Primary Citation*

    A. Wilm, P. P. Aw, D. Bertrand, G. H. Yeo, S. H. Ong, C. H. Wong, C. C. Khor, R. Petric, M. L. Hibberd, and N. N.. 2012. LoFreq: a sequence-quality aware, ultra-sensitive variant caller for uncovering cell-population heterogeneity from high-throughput sequencing datasets. Nucleic Acids Res.. 40(22): 11189-11201.

    • *Full citation information available through