a command line tool for estimating heritability and genetic correlation from GWAS summary statistics. ldsc also computes LD Scores.
BioGrids installed LDSC provides the following executables:
ldsc (an alias for ldsc.py)
munge_sumstats (an alias for munge_sumstats.py)
python.ldsc (the python included with BioGrids LDSC)
InstallationUse the following command to install this title with the CLI client:
$ biogrids-cli install ldsc
B. K. Bulik-Sullivan, P. R. Loh, H. K. Finucane, S. Ripke, J. Yang, Schizophrenia-Working-Group-of-the-Psychiatric-Genomics-Consortium, N. Patterson, M. J. Daly, A. L. Price, and B. M. Neale. 2015. LD Score regression distinguishes confounding from polygenicity in genome-wide association studies. Nat Genet.. 47(3): 291-295.
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