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Supported Applications

Eagle

  • Description

    estimates haplotype phase either within a genotyped cohort or using a phased reference panel. Eagle2 is now the default phasing method used by the Sanger and Michigan imputation servers and uses a new, very fast HMM-based algorithm that improves speed and accuracy over existing methods via two key ideas: a new data structure based on the positional Burrows-Wheeler transform and a rapid search algorithm that explores only the most relevant paths through the HMM.

  • Usage

    To list all executables provided by Eagle, run: $ biogrids-list eagle Copy to clipboard
  • Installation

    Use the following command to install this title with the CLI client: $ biogrids-cli install eagle Copy to clipboard Available operating systems: Linux 64
  • Primary Citation*

    P.-R. Loh, P. Danecek, P. F. Palamara, C. Fuchsberger, Y. A. Reshef, H. K. Finucane, S. Schoenherr, L. Forer, S. McCarthy, G. R. Abecasis, R. Durbin, and A. L. Price. 2016. Reference-based phasing using the Haplotype Reference Consortium panel. Nat Genet. 48(11): 1443-1448.


    • *Full citation information available through

  • Keywords

    Genomics

  • Default Versions

    Linux 64:  2.4.1 (218.1 MB)

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