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CHISEL

  • Description

    Copy-number Haplotype Inference in Single-cell by Evolutionary Links

    CHISEL is an algorithm to infer allele- and haplotype-specific copy numbers in individual cells from low-coverage single-cell DNA sequencing data (e.g., those generated by Direct Library Preparation+ (DLP+), 10x Genomics CNV Solution, DOP-PCR, etc.).

  • Usage

    To list all executables provided by CHISEL, run: $ biogrids-list chisel Copy to clipboard

  • Installation

    Use the following command to install this title with the CLI client: $ biogrids-cli install chisel Copy to clipboard Available operating systems: Linux 64, OS X INTEL

  • Primary Citation*

    S. Zaccaria and B. J. Raphael. 2021. Characterizing allele- and haplotype-specific copy numbers in single cells with CHISEL. Nature biotechnology. 39(2): 207-214.


    • *Full citation information available through

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